Intracellular regulation of ion channels in cell membranes

D. L. Lewis, James D Lechleiter, D. Kim, C. Nanavati, D. E. Clapham

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Cells communicate with their environment through receptor proteins on the cell membrane. Some ion channels are receptors, whereas others are linked to receptors through guanine nucleotide-binding proteins (G proteins). Ion channels control intracellular concentrations of ions such as calcium, and these concentrations control cell functions such as secretion and cell division. This review summarizes the current state of knowledge about the control of ion channels.

Original languageEnglish (US)
Pages (from-to)1127-1143
Number of pages17
JournalMayo Clinic Proceedings
Volume65
Issue number8
StatePublished - 1990
Externally publishedYes

Fingerprint

Ion Channels
Cell Membrane
Guanine Nucleotides
GTP-Binding Proteins
Cell Division
Carrier Proteins
Membrane Proteins
Ions
Calcium

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lewis, D. L., Lechleiter, J. D., Kim, D., Nanavati, C., & Clapham, D. E. (1990). Intracellular regulation of ion channels in cell membranes. Mayo Clinic Proceedings, 65(8), 1127-1143.

Intracellular regulation of ion channels in cell membranes. / Lewis, D. L.; Lechleiter, James D; Kim, D.; Nanavati, C.; Clapham, D. E.

In: Mayo Clinic Proceedings, Vol. 65, No. 8, 1990, p. 1127-1143.

Research output: Contribution to journalArticle

Lewis, DL, Lechleiter, JD, Kim, D, Nanavati, C & Clapham, DE 1990, 'Intracellular regulation of ion channels in cell membranes', Mayo Clinic Proceedings, vol. 65, no. 8, pp. 1127-1143.
Lewis DL, Lechleiter JD, Kim D, Nanavati C, Clapham DE. Intracellular regulation of ion channels in cell membranes. Mayo Clinic Proceedings. 1990;65(8):1127-1143.
Lewis, D. L. ; Lechleiter, James D ; Kim, D. ; Nanavati, C. ; Clapham, D. E. / Intracellular regulation of ion channels in cell membranes. In: Mayo Clinic Proceedings. 1990 ; Vol. 65, No. 8. pp. 1127-1143.
@article{5d98622fe646468f916fef11f61cc290,
title = "Intracellular regulation of ion channels in cell membranes",
abstract = "Cells communicate with their environment through receptor proteins on the cell membrane. Some ion channels are receptors, whereas others are linked to receptors through guanine nucleotide-binding proteins (G proteins). Ion channels control intracellular concentrations of ions such as calcium, and these concentrations control cell functions such as secretion and cell division. This review summarizes the current state of knowledge about the control of ion channels.",
author = "Lewis, {D. L.} and Lechleiter, {James D} and D. Kim and C. Nanavati and Clapham, {D. E.}",
year = "1990",
language = "English (US)",
volume = "65",
pages = "1127--1143",
journal = "Mayo Clinic Proceedings",
issn = "0025-6196",
publisher = "Elsevier Science",
number = "8",

}

TY - JOUR

T1 - Intracellular regulation of ion channels in cell membranes

AU - Lewis, D. L.

AU - Lechleiter, James D

AU - Kim, D.

AU - Nanavati, C.

AU - Clapham, D. E.

PY - 1990

Y1 - 1990

N2 - Cells communicate with their environment through receptor proteins on the cell membrane. Some ion channels are receptors, whereas others are linked to receptors through guanine nucleotide-binding proteins (G proteins). Ion channels control intracellular concentrations of ions such as calcium, and these concentrations control cell functions such as secretion and cell division. This review summarizes the current state of knowledge about the control of ion channels.

AB - Cells communicate with their environment through receptor proteins on the cell membrane. Some ion channels are receptors, whereas others are linked to receptors through guanine nucleotide-binding proteins (G proteins). Ion channels control intracellular concentrations of ions such as calcium, and these concentrations control cell functions such as secretion and cell division. This review summarizes the current state of knowledge about the control of ion channels.

UR - http://www.scopus.com/inward/record.url?scp=0024986239&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024986239&partnerID=8YFLogxK

M3 - Article

C2 - 1697015

AN - SCOPUS:0024986239

VL - 65

SP - 1127

EP - 1143

JO - Mayo Clinic Proceedings

JF - Mayo Clinic Proceedings

SN - 0025-6196

IS - 8

ER -