Interpretive criteria and quality control parameters for testing bacterial susceptibility to the fluoroquinolone PD131628

A. L. Barry, P. C. Fuchs, S. D. Allen, F. C. Tenover, J. H. Jorgensen, L. B. Reller

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Abstract

For testing bacterial susceptibility to PD131628, a 5-μg disk and the following tentative interpretative criteria may be used: ≥19 mm for susceptible (MIC, ≤1.0 μg/ml), 16 to 18 mm for intermediate (MIC, 2.0 μg/ml), and ≤15 mm for resistant (MIC, ≥4.0 μg/ml). For standard quality control strains, the following limits are proposed: for Escherichia coli ATCC 25922, zones of 31 to 41 mm or a MIC of 0.002 to 0.016 μg/ml; for Pseudomonas aeruginosa ATCC 27853, zones of 26 to 34 mm or a MIC of 0.12 to 0.5 μg/ml; for Staphylococcus aureus ATCC 25923, zones of 27 to 33 mm; for Staphylococcus aureus ATCC 29213, a MIC of 0.03 to 0.12 μg/ml; and for Enterococcus faecalis ATCC 29212, a MIC of 0.12 to 0.5 μg/ml.

Original languageEnglish (US)
Pages (from-to)235-238
Number of pages4
JournalJournal of clinical microbiology
Volume33
Issue number1
StatePublished - Jan 1 1995

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ASJC Scopus subject areas

  • Microbiology (medical)

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Barry, A. L., Fuchs, P. C., Allen, S. D., Tenover, F. C., Jorgensen, J. H., & Reller, L. B. (1995). Interpretive criteria and quality control parameters for testing bacterial susceptibility to the fluoroquinolone PD131628. Journal of clinical microbiology, 33(1), 235-238.