Interlaboratory studies and initiatives developing standards for proteomics

Alexander R. Ivanov, Christopher M. Colangelo, Craig P. Dufresne, David B. Friedman, Kathryn S. Lilley, Karl Mechtler, Brett S. Phinney, Kristie L. Rose, Paul A. Rudnick, Brian C. Searle, Scott A. Shaffer, Susan T. Weintraub

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Proteomics is a rapidly transforming interdisciplinary field of research that embraces a diverse set of analytical approaches to tackle problems in fundamental and applied biology. This viewpoint article highlights the benefits of interlaboratory studies and standardization initiatives to enable investigators to address many of the challenges found in proteomics research. Among these initiatives, we discuss our efforts on a comprehensive performance standard for characterizing PTMs by MS that was recently developed by the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG).

Original languageEnglish (US)
Pages (from-to)904-909
Number of pages6
Issue number6
StatePublished - Mar 2013


  • LC-MS/MS
  • Mass spectrometry-based proteomics
  • Phosphopeptides
  • Post-translational modifications
  • Protein identification

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology


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