Interlaboratory studies and initiatives developing standards for proteomics

Alexander R. Ivanov; Christopher M. Colangelo; Craig P. Dufresne; David B. Friedman; Kathryn S. Lilley; Karl Mechtler; Brett S. Phinney; Kristie L. Rose; Paul A. Rudnick; Brian C. Searle; Scott A. Shaffer; Susan T. Weintraub

doi:10.1002/pmic.201200532

Interlaboratory studies and initiatives developing standards for proteomics

Alexander R. Ivanov, Christopher M. Colangelo, Craig P. Dufresne, David B. Friedman, Kathryn S. Lilley, Karl Mechtler, Brett S. Phinney, Kristie L. Rose, Paul A. Rudnick, Brian C. Searle, Scott A. Shaffer, Susan T. Weintraub

Department of Biochemistry & Structural Biology

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Proteomics is a rapidly transforming interdisciplinary field of research that embraces a diverse set of analytical approaches to tackle problems in fundamental and applied biology. This viewpoint article highlights the benefits of interlaboratory studies and standardization initiatives to enable investigators to address many of the challenges found in proteomics research. Among these initiatives, we discuss our efforts on a comprehensive performance standard for characterizing PTMs by MS that was recently developed by the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG).

Original language	English (US)
Pages (from-to)	904-909
Number of pages	6
Journal	Proteomics
Volume	13
Issue number	6
DOIs	https://doi.org/10.1002/pmic.201200532
State	Published - Mar 2013

Keywords

LC-MS/MS
Mass spectrometry-based proteomics
Phosphopeptides
Post-translational modifications
Protein identification

ASJC Scopus subject areas

Molecular Biology
Biochemistry

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10.1002/pmic.201200532

Cite this

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title = "Interlaboratory studies and initiatives developing standards for proteomics",

abstract = "Proteomics is a rapidly transforming interdisciplinary field of research that embraces a diverse set of analytical approaches to tackle problems in fundamental and applied biology. This viewpoint article highlights the benefits of interlaboratory studies and standardization initiatives to enable investigators to address many of the challenges found in proteomics research. Among these initiatives, we discuss our efforts on a comprehensive performance standard for characterizing PTMs by MS that was recently developed by the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG).",

keywords = "LC-MS/MS, Mass spectrometry-based proteomics, Phosphopeptides, Post-translational modifications, Protein identification",

author = "Ivanov, {Alexander R.} and Colangelo, {Christopher M.} and Dufresne, {Craig P.} and Friedman, {David B.} and Lilley, {Kathryn S.} and Karl Mechtler and Phinney, {Brett S.} and Rose, {Kristie L.} and Rudnick, {Paul A.} and Searle, {Brian C.} and Shaffer, {Scott A.} and Weintraub, {Susan T.}",

year = "2013",

month = mar,

doi = "10.1002/pmic.201200532",

language = "English (US)",

volume = "13",

pages = "904--909",

journal = "Proteomics",

issn = "1615-9853",

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T1 - Interlaboratory studies and initiatives developing standards for proteomics

AU - Ivanov, Alexander R.

AU - Colangelo, Christopher M.

AU - Dufresne, Craig P.

AU - Friedman, David B.

AU - Lilley, Kathryn S.

AU - Mechtler, Karl

AU - Phinney, Brett S.

AU - Rose, Kristie L.

AU - Rudnick, Paul A.

AU - Searle, Brian C.

AU - Shaffer, Scott A.

AU - Weintraub, Susan T.

PY - 2013/3

Y1 - 2013/3

N2 - Proteomics is a rapidly transforming interdisciplinary field of research that embraces a diverse set of analytical approaches to tackle problems in fundamental and applied biology. This viewpoint article highlights the benefits of interlaboratory studies and standardization initiatives to enable investigators to address many of the challenges found in proteomics research. Among these initiatives, we discuss our efforts on a comprehensive performance standard for characterizing PTMs by MS that was recently developed by the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG).

AB - Proteomics is a rapidly transforming interdisciplinary field of research that embraces a diverse set of analytical approaches to tackle problems in fundamental and applied biology. This viewpoint article highlights the benefits of interlaboratory studies and standardization initiatives to enable investigators to address many of the challenges found in proteomics research. Among these initiatives, we discuss our efforts on a comprehensive performance standard for characterizing PTMs by MS that was recently developed by the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG).

KW - LC-MS/MS

KW - Mass spectrometry-based proteomics

KW - Phosphopeptides

KW - Post-translational modifications

KW - Protein identification

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Interlaboratory studies and initiatives developing standards for proteomics

Abstract

Keywords

ASJC Scopus subject areas

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