Interferon-induced sarcoidosis

Mittie K. Doyle; Ruth Berggren; Jeanette H. Magnus

doi:10.1097/01.rhu.0000240035.67652.9d

Interferon-induced sarcoidosis

Mittie K. Doyle, Ruth Berggren, Jeanette H. Magnus

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis. We present a case of a 59-year-old former intravenous drug user who developed systemic sarcoidosis while receiving interferon alpha and ribavirin for the treatment of chronic hepatitis C. Because interferons are increasingly prescribed by specialists in a variety of disciplines, rheumatologists should be aware of their potential to induce sarcoidosis as well as various autoimmune diseases.

Original language	English (US)
Pages (from-to)	241-248
Number of pages	8
Journal	Journal of Clinical Rheumatology
Volume	12
Issue number	5
DOIs	https://doi.org/10.1097/01.rhu.0000240035.67652.9d
State	Published - Oct 1 2006
Externally published	Yes

Keywords

Autoimmunity
Hepatitis C
Interferon
Sarcoidosis

ASJC Scopus subject areas

Rheumatology

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AB - Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis. We present a case of a 59-year-old former intravenous drug user who developed systemic sarcoidosis while receiving interferon alpha and ribavirin for the treatment of chronic hepatitis C. Because interferons are increasingly prescribed by specialists in a variety of disciplines, rheumatologists should be aware of their potential to induce sarcoidosis as well as various autoimmune diseases.

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Interferon-induced sarcoidosis

Abstract

Keywords

ASJC Scopus subject areas

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