Abstract
Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis. We present a case of a 59-year-old former intravenous drug user who developed systemic sarcoidosis while receiving interferon alpha and ribavirin for the treatment of chronic hepatitis C. Because interferons are increasingly prescribed by specialists in a variety of disciplines, rheumatologists should be aware of their potential to induce sarcoidosis as well as various autoimmune diseases.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 241-248 |
| Number of pages | 8 |
| Journal | Journal of Clinical Rheumatology |
| Volume | 12 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 2006 |
| Externally published | Yes |
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Keywords
- Autoimmunity
- Hepatitis C
- Interferon
- Sarcoidosis
ASJC Scopus subject areas
- Rheumatology
Cite this
Interferon-induced sarcoidosis. / Doyle, Mittie K.; Berggren, Ruth E; Magnus, Jeanette H.
In: Journal of Clinical Rheumatology, Vol. 12, No. 5, 10.2006, p. 241-248.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Interferon-induced sarcoidosis
AU - Doyle, Mittie K.
AU - Berggren, Ruth E
AU - Magnus, Jeanette H.
PY - 2006/10
Y1 - 2006/10
N2 - Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis. We present a case of a 59-year-old former intravenous drug user who developed systemic sarcoidosis while receiving interferon alpha and ribavirin for the treatment of chronic hepatitis C. Because interferons are increasingly prescribed by specialists in a variety of disciplines, rheumatologists should be aware of their potential to induce sarcoidosis as well as various autoimmune diseases.
AB - Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis. We present a case of a 59-year-old former intravenous drug user who developed systemic sarcoidosis while receiving interferon alpha and ribavirin for the treatment of chronic hepatitis C. Because interferons are increasingly prescribed by specialists in a variety of disciplines, rheumatologists should be aware of their potential to induce sarcoidosis as well as various autoimmune diseases.
KW - Autoimmunity
KW - Hepatitis C
KW - Interferon
KW - Sarcoidosis
UR - http://www.scopus.com/inward/record.url?scp=33749527090&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749527090&partnerID=8YFLogxK
U2 - 10.1097/01.rhu.0000240035.67652.9d
DO - 10.1097/01.rhu.0000240035.67652.9d
M3 - Article
C2 - 17023810
AN - SCOPUS:33749527090
VL - 12
SP - 241
EP - 248
JO - Journal of Clinical Rheumatology
JF - Journal of Clinical Rheumatology
SN - 1076-1608
IS - 5
ER -