Interferon-induced sarcoidosis

Mittie K. Doyle, Ruth Berggren, Jeanette H. Magnus

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis. We present a case of a 59-year-old former intravenous drug user who developed systemic sarcoidosis while receiving interferon alpha and ribavirin for the treatment of chronic hepatitis C. Because interferons are increasingly prescribed by specialists in a variety of disciplines, rheumatologists should be aware of their potential to induce sarcoidosis as well as various autoimmune diseases.

Original languageEnglish (US)
Pages (from-to)241-248
Number of pages8
JournalJournal of Clinical Rheumatology
Volume12
Issue number5
DOIs
StatePublished - Oct 1 2006
Externally publishedYes

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Keywords

  • Autoimmunity
  • Hepatitis C
  • Interferon
  • Sarcoidosis

ASJC Scopus subject areas

  • Rheumatology

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