Abstract
NK activity was evaluated in three patients with chronic granulomatous disease (CGD), a disorder in which phagocytic cells fail to undergo a stimulus-dependent burst of oxidative metabolism and thus do not generate toxic oxygen derivatives. In spite of the inability to produce reactive oxygen species, CGD mononuclear cells have normal NK activity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 569-570 |
| Number of pages | 2 |
| Journal | Journal of Immunology |
| Volume | 132 |
| Issue number | 2 |
| State | Published - 1984 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Immunology
Cite this
Intact natural killer activity in chronic granulomatous disease : Evidence against an oxygen-dependent cytotoxic mechanism. / El Hag, A.; Clark, Robert A.
In: Journal of Immunology, Vol. 132, No. 2, 1984, p. 569-570.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intact natural killer activity in chronic granulomatous disease
T2 - Evidence against an oxygen-dependent cytotoxic mechanism
AU - El Hag, A.
AU - Clark, Robert A
PY - 1984
Y1 - 1984
N2 - NK activity was evaluated in three patients with chronic granulomatous disease (CGD), a disorder in which phagocytic cells fail to undergo a stimulus-dependent burst of oxidative metabolism and thus do not generate toxic oxygen derivatives. In spite of the inability to produce reactive oxygen species, CGD mononuclear cells have normal NK activity.
AB - NK activity was evaluated in three patients with chronic granulomatous disease (CGD), a disorder in which phagocytic cells fail to undergo a stimulus-dependent burst of oxidative metabolism and thus do not generate toxic oxygen derivatives. In spite of the inability to produce reactive oxygen species, CGD mononuclear cells have normal NK activity.
UR - http://www.scopus.com/inward/record.url?scp=0021369297&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021369297&partnerID=8YFLogxK
M3 - Article
VL - 132
SP - 569
EP - 570
JO - Journal of Immunology
JF - Journal of Immunology
SN - 0022-1767
IS - 2
ER -