Insulin secretion, insulin resistance, and obesity

Research output: Contribution to journalArticlepeer-review

103 Scopus citations


Insulin resistance and hyperinsulinemia are present in the majority of obese subjects if they are over 50% of ideal body weight. The insulin resistance is manifested by decreased uptake of glucose by peripheral tissues (muscle) and impaired suppression of hepatic glucose production. Both of these abnormalities can be improved by physical training.

Original languageEnglish (US)
Pages (from-to)73-82
Number of pages10
JournalInternational Journal of Obesity
Issue numberSuppl. 1
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics


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