Insulin secretion, insulin resistance, and obesity

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Abstract

Insulin resistance and hyperinsulinemia are present in the majority of obese subjects if they are over 50% of ideal body weight. The insulin resistance is manifested by decreased uptake of glucose by peripheral tissues (muscle) and impaired suppression of hepatic glucose production. Both of these abnormalities can be improved by physical training.

Original languageEnglish (US)
Pages (from-to)73-82
Number of pages10
JournalInternational Journal of Obesity
Volume6
Issue numberSuppl. 1
Publication statusPublished - Dec 1 1982

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ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

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