The insulin degrading activity of fat cell ghosts prepared from obese rats was equivalent to those prepared from normal rats. Normal human fat cell ghosts exhibited much less activity than the normal fat cell ghost. Due to the ubiquitous distribution of adipose tissue and the substantial insulin degrading activity observed, it would appear that this tissue may play an important role in insulin turnover in the body.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Clinical Biochemistry
- Biochemistry, medical