Institutional performance in application of the FAB classification of acute leukemia. The southwest oncology group experience

David R. Head, Catherine M. Craven, Lizardo Cerezo, Richard A. Savage, John N. Bickers, Robert Hartsock, Thomas A. Hosty, John H. Saiki, Henry E. Wilson, Francis S. Morrison, Charles A. Coltman, John J. Hutton

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Institutional performance in application of the French‐American‐British (FAB) classification of acute leukemia in The Southwest Oncology Group is presented, demonstrating a disparity between institutional and expert performance. A significant improvement is shown with an educational effort coupled with experience in use of the classification, and the importance of cytochemistry in the use of the classification is illustrated. A simplification of the classification, merging M1, M2, and M4 as M7, is proposed. This simplification improves institutional performance in use of the classification, while preserving distinctions that appear clinically important.

Original languageEnglish (US)
Pages (from-to)1979-1986
Number of pages8
JournalCancer
Volume55
Issue number9
DOIs
StatePublished - May 1 1985
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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