Injectable, biodegradable PEG copolyester as a carrier for endothelial cells

L. J. Suggs, C. A. Garcia, A. G. Mikos

Research output: Contribution to conferencePaperpeer-review

Abstract

A block copolymer of poly(propylene fumarate-co-ethylene glycol), P(PF-co-EG) was developed in order to address problems with currently used cardiovascular stenting materials. P(PF-co-EG) is crosslinkable through the fumarate double bonds forming a mechanically stable hydrogel which degrades into fumaric acid, propylene glycol and PEG. Because of these properties, P(PF-co-EG) has potential for use as an injectable, biodegradable implant. Embedding of endothelial cells during the crosslinkable process was proposed and the feasibility of using this material as a carrier for endothelial cells was assessed. The cytotoxicity of preformed copolymer disks was examined as well as cell viability upon embedding.

Original languageEnglish (US)
Pages66
Number of pages1
StatePublished - 1998
Externally publishedYes
EventProceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA
Duration: Feb 6 1998Feb 8 1998

Other

OtherProceedings of the 1998 17th Southern Biomedical Engineering Conference
CitySan Antonio, TX, USA
Period2/6/982/8/98

ASJC Scopus subject areas

  • Engineering(all)

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