Abstract
Diallyl sulfide (DAS), one of a number of organosulfur compounds accounting for the flavor and smell associated with garlic, has been shown to inhibit a number of chemically induced forms of cancer. In this study, DAS was examined for its chemopreventive effects in both the initiation and post-initiation phases of nitrosomethylbenzylamine-induced esophageal carcinogenesis in the Sprague - Dawley rat. Although highly inhibitory during initiation, DAS is ineffective when given after the carcinogen. DAS, though not effective as a preventive in post-initiation, was not found to promote esophageal carcinogenesis.
Original language | English (US) |
---|---|
Pages (from-to) | 39-42 |
Number of pages | 4 |
Journal | Cancer Letters |
Volume | 64 |
Issue number | 1 |
DOIs | |
State | Published - May 30 1992 |
Keywords
- alliums
- chemoprevention
- diallyl sulfide
- esophageal cancer
ASJC Scopus subject areas
- Oncology
- Cancer Research