Inhibition of phosphatidylinostol 3-kinase uncouples H₂O ₂-induced senescent phenotype and cell cycle arrest in normal human diploid fibroblasts

Biochemistry, Genetics and Molecular Biology

• Cell Cycle Arrest 100%
• Fibroblast 80%
• Phenotype 80%
• Kinase 80%
• Senescence 80%
• Morphology 40%
• Galactosidase 40%
• P38 Mitogen-Activated Protein Kinases 40%
• Normal Human 20%
• Mitogen-Activated Protein Kinase Kinase 20%
• P53 20%
• Retinoblastoma Protein 20%
• Hydrogen Peroxide 20%
• LY294002 20%
• P21 20%
• Diploidy 20%
• Contrast 20%
• P14arf 20%
• Cell Enlargement 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Cell Cycle 100%
• Phosphotransferase 80%
• Hydrogen Peroxide 60%
• Mitogen Activated Protein Kinase P38 40%
• Galactosidase 40%
• Retinoblastoma Protein 40%
• Normal Human 20%
• 2 (2 Amino 3 Methoxyphenyl)chromone 20%
• Prematurity 20%
• Protein P53 20%
• 2 Morpholino 8 Phenylchromone 20%
• Mitogen Activated Protein Kinase Kinase 20%
• SB 203580 20%