Inhibition of luteinizing hormone release and ovulation in PMS-treated rats by peripherally administered melatonin

R. J. Reiter; S. Sorrentino

doi:10.1016/0010-7824(71)90053-9

Inhibition of luteinizing hormone release and ovulation in PMS-treated rats by peripherally administered melatonin

R. J. Reiter, S. Sorrentino

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Abstract

The influence of intraperitoneally administered melatonin on ovulation and the plasma content of luteinizing hormone in pregnant mare's serum (PMS) treated immature rats was tested. Melatonin, administered in three equivalent doses of 500 μg each at 2:00, 3:00 and 4:00 P. M. on the second day after PMS administration, reduced the number of rats that ovulated. Melatonin also prevented the rise in plasma luteinizing hormone which occurred in the majority of the control animals at 57 hours after PMS administration.

Original language	English (US)
Pages (from-to)	385-392
Number of pages	8
Journal	Contraception
Volume	4
Issue number	6
DOIs	https://doi.org/10.1016/0010-7824(71)90053-9
State	Published - Dec 1971
Externally published	Yes

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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10.1016/0010-7824(71)90053-9

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abstract = "The influence of intraperitoneally administered melatonin on ovulation and the plasma content of luteinizing hormone in pregnant mare's serum (PMS) treated immature rats was tested. Melatonin, administered in three equivalent doses of 500 μg each at 2:00, 3:00 and 4:00 P. M. on the second day after PMS administration, reduced the number of rats that ovulated. Melatonin also prevented the rise in plasma luteinizing hormone which occurred in the majority of the control animals at 57 hours after PMS administration.",

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AU - Reiter, R. J.

AU - Sorrentino, S.

PY - 1971/12

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N2 - The influence of intraperitoneally administered melatonin on ovulation and the plasma content of luteinizing hormone in pregnant mare's serum (PMS) treated immature rats was tested. Melatonin, administered in three equivalent doses of 500 μg each at 2:00, 3:00 and 4:00 P. M. on the second day after PMS administration, reduced the number of rats that ovulated. Melatonin also prevented the rise in plasma luteinizing hormone which occurred in the majority of the control animals at 57 hours after PMS administration.

AB - The influence of intraperitoneally administered melatonin on ovulation and the plasma content of luteinizing hormone in pregnant mare's serum (PMS) treated immature rats was tested. Melatonin, administered in three equivalent doses of 500 μg each at 2:00, 3:00 and 4:00 P. M. on the second day after PMS administration, reduced the number of rats that ovulated. Melatonin also prevented the rise in plasma luteinizing hormone which occurred in the majority of the control animals at 57 hours after PMS administration.

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Inhibition of luteinizing hormone release and ovulation in PMS-treated rats by peripherally administered melatonin

Abstract

ASJC Scopus subject areas

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