Abstract
Aurintricarboxylic acid is a potent inhibitor of cell-free protein synthesis by the post-mitochondrial supernatant of chick brain and the translation of mRNA by wheat germ lysate. Comparison of commercially available and chemically synthesized analogues of aurintricarboxylic acid indicates that the unique aurin triphenyl methane ring system and the carboxylic acid groups are both necessary for inhibition of cell-free protein synthesis in both systems.
Original language | English (US) |
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Pages (from-to) | 1162-1167 |
Number of pages | 6 |
Journal | Canadian journal of biochemistry |
Volume | 56 |
Issue number | 12 |
DOIs | |
State | Published - Dec 1978 |
ASJC Scopus subject areas
- Medicine(all)