Abstract
The attachment of endometrial epithelial cells (EECs) and endometrial stromal cells (ESCs) to peritoneal mesothelial cells (PMCs) with and without inhibition of N- and O-linked glycosylation, the viability of EECs and ESCs, and the expression of CD44 surface density were evaluated. Inhibition of CD44 N- and O-linked glycosylation by using tunicamycin and/or B-GalNAc statistically significantly inhibited endometrial cell attachment to peritoneal mesothelial cells, suggesting a role in establishment of early endometriotic lesions.
Original language | English (US) |
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Pages (from-to) | 823-825 |
Number of pages | 3 |
Journal | Fertility and sterility |
Volume | 95 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2011 |
Keywords
- CD44
- endometriosis
- glycosylation
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology