Inhibition by plant phenols of benzo[a]pyrene-induced nuclear aberrations in mammalian intestinal cells: A rapid in vivo assessment method

M. J. Wargovich, V. W.S. Eng, H. L. Newmark

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

The polycyclic aromatic hydrocarbon, benzo[a]pyrene, induced dose-related nuclear damage (micronuclei, pyknotic nuclei and karyorrhectic bodies) in colonic epithelial cells of C57BL/6J mice within 24 hr when administered intrarectally in single doses of 0-200 mg/kg body weight. This damage was.

Original languageEnglish (US)
Pages (from-to)47-49
Number of pages3
JournalFood and Chemical Toxicology
Volume23
Issue number1
DOIs
StatePublished - Jan 1985
Externally publishedYes

ASJC Scopus subject areas

  • Food Science
  • Toxicology

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