Influences of age and exercise on glucose metabolism: Implications for management of older diabetics

M. S. Katz, D. T. Lowenthal

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The well-characterized decline in glucose tolerance during aging is due primarily to impaired insulin-mediated glucose uptake in peripheral tissues. Elderly persons with reduced insulin sensitivity are predisposed to the development of non-insulin-dependent diabetes mellitus (NIDDM), which is common in the geriatric population. Numerous studies suggest that exercise and physical training increase insulin sensitivity in young adult and middle- aged nondiabetics, older subjects with impaired glucose tolerance, and middle-aged persons with NIDDM. These investigations provide presumptive evidence that elderly persons with NIDDM may benefit from exercise training, although no published studies have specifically addressed the effects of exercise in older diabetics. Physical activity may also be effective in preventing the development of NIDDM. In addition, exercise training improves several cardiovascular risk factors, such as plasma lipid abnormalities, hypertension, and obesity. The risks of exercise in older diabetics include hypoglycemia in insulin-treated patients, exacerbation of preexisting cardiovascular disease, and worsening of long-term diabetic complications. Any exercise prescription in the older diabetic must be individualized to the patient's physical capabilities, limitations, and preferences.

Original languageEnglish (US)
JournalSouthern Medical Journal
Volume87
Issue number5
StatePublished - 1994

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Exercise
Glucose
Type 2 Diabetes Mellitus
Insulin Resistance
Insulin
Preexisting Condition Coverage
Glucose Intolerance
Diabetes Complications
Hypoglycemia
Geriatrics
Prescriptions
Young Adult
Cardiovascular Diseases
Obesity
Hypertension
Lipids
Population

ASJC Scopus subject areas

  • Medicine(all)

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Influences of age and exercise on glucose metabolism : Implications for management of older diabetics. / Katz, M. S.; Lowenthal, D. T.

In: Southern Medical Journal, Vol. 87, No. 5, 1994.

Research output: Contribution to journalArticle

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