Influence of ovariectomy and estrogen and/or progesterone treatment on pituitary and plasma lh and prolactin levels in female hamsters

R. J. Reiter, D. E. Blask, L. Y. Johnson

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Ovariectomy in adult female hamsters caused a highly significant elevation in pituitary luteinizing hormone (LH) and a highly significant reduction in pituitary prolactin levels. Likewise, loss of the ovaries was followed by a rise in plasma levels of LH while plasma prolactin titers dropped. Treatment of ovariectomized hamsters with estrogen (E) or progesterone (P), alone or in combination, did not greatly influence LH or prolactin levels in the pituitary. Whereas P, when administered alone or with E, returned plasma LH levels to normal, E by itself had no effect on LH levels in ovariectomized hamsters. Neither E nor P had any influence on the reduced plasma prolactin levels in ovariectomized female hamsters.

Original languageEnglish (US)
Pages (from-to)181-191
Number of pages11
JournalEndocrine Research
Volume1
Issue number2
DOIs
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Endocrinology

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