Influence of enteric nutrition on blood urea nitrogen (BUN) in very old patients with chronic kidney disease (CKD)

Linda Shavit, Meyer Lifschitz, Ilia Galperin

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


The purpose was to check the influence of enteric nutrition on BUN in very elderly patients. Clinical data on patients in whom enteral feeding was initiated after a period of poor oral intake are presented. Patients with evidence of volume depletion, signs of gastrointestinal bleeding or medicines that might increase BUN were excluded. We evaluated 5 patients (mean age 90.6±3 years) who were admitted to geriatric department. Mean plasma creatinine concentration was 1.17±0.34mg/dl, but mean estimated glomerular filtration rate (eGFR) was 41.6±17ml/min/1.73m 2. Enteral nutrition was administered at a dose of mean 1580±53ml/day at mean duration of 9±4 days. Mean BUN was 52±30mg/dl at baseline, increases to 109±9.4mg/dl after initiation of feeding and decreased to 82±1.1mg/dl with reduction of dose of enteral nutrition. Our conclusion was that initiation of enteral feeding may induce a large accumulation of nitrogen waste products in elderly patients in whom serum creatinine is an unreliable indicator of kidney function. High protein intake should be considered in differential diagnosis of disproportionate high increment of BUN.

Original languageEnglish (US)
Pages (from-to)228-231
Number of pages4
JournalArchives of Gerontology and Geriatrics
Issue number1
StatePublished - Jan 2012
Externally publishedYes


  • Blood urea nitrogen (BUN)
  • Chronic kidney disease (CKD)
  • Enteric nutrition in very elderly

ASJC Scopus subject areas

  • Health(social science)
  • Aging
  • Gerontology
  • Geriatrics and Gerontology


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