Influence of Anatomic Distribution of Atherosclerosis on the Outcome of Revascularization with Iliac Stent Placement

Purpose: To determine the influence of clinical and angiographic variables, including the anatomic disease pattern, on the outcome of iliac stent placement. Patients and Methods: The 455 patients of the study population were divided in three groups according to the anatomic distribution of their peripheral atherosclerosis lesions. Pattern type 1 (focal aortoiliac and/or common iliac lesion) included 180 patients (39.6%), type 2 (external iliac lesion) comprised 58 patients (12.8%), and type 3 (multilevel lesions) included 217 patients (47.7%). Results: Complete relief of symptoms immediately after revascularization was observed in 88.3% and 85.4% of patients with pattern type 1 and 2, respectively, compared to 60.1% with type 3 (P < .05). The persistence of clinical benefit at 36-month follow-up was 91.6%, 97.9%, and 60.8% in disease patterns 1, 2, and 3, respectively. The overall 1-year mortality rate was 3% with type 1 lesions, 5.7% with type 2, and 9.7% with type 3. On multivariate logistic regression, the presence of a disease pattern type 3 was the most powerful indicator (P < .001) of early unsatisfactory clinical outcome in iliac stent placement. Unexpectedly, female gender was predictive of unsatisfactory clinical outcome (P < .01) and higher periprocedural complications (P < .001) following iliac stent revascularization. Conclusions: Pattern type classification helps identify patients at higher risk for cardiovascular morbidity and mortality. Ideal candidates for iliac stent placement are patients with pattern type 1 or 2 disease.