Infectious causes of stillbirth: A clinical perspective

Elizabeth M. McClure, Donald J. Dudley, Uma M. Reddy, Robert L. Goldenberg

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations

Abstract

Untreated infection may cause stillbirth by several mechanisms, including direct fetal infection, placental damage, and severe maternal illness. Many bacteria, viruses, and protozoa have been associated with stillbirth. In developed countries, up to 24% of stillbirths have been attributed to infection, although with increased availability of sophisticated diagnostics and rigorous screening, it appears likely that higher numbers may actually be associated with infection. In developed countries, ascending bacterial infection is usually the most common infectious cause of stillbirth, with a number of viral infections also an important factor. Screening, prevention, and treatment of maternal infections are important to reduce stillbirth risk.

Original languageEnglish (US)
Pages (from-to)635-645
Number of pages11
JournalClinical Obstetrics and Gynecology
Volume53
Issue number3
DOIs
StatePublished - Sep 2010
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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