Infection of a Laboratory Worker with Simian Immunodeficiency Virus

Rima F. Khabbaz; Walid Heneine; J. Richard George; Bharat Parekh; Thomas Rowe; Toni Woods; William M. Switzer; Harold M. Mcclure; Michael Murphey-Corb; Thomas M. Folks

doi:10.1056/NEJM199401203300304

Infection of a Laboratory Worker with Simian Immunodeficiency Virus

Rima F. Khabbaz, Walid Heneine, J. Richard George, Bharat Parekh, Thomas Rowe, Toni Woods, William M. Switzer, Harold M. Mcclure, Michael Murphey-Corb, Thomas M. Folks

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

Abstract

Simian immunodeficiency viruses (SIVs) are primate lentiviruses that are morphologically similar and biologically related to human immunodeficiency viruses (HIVs)¹–⁴. SIVs naturally infect some nonhuman primate species, such as African green monkeys and sooty mangabey monkeys, without causing immunodeficiency. In contrast, experimental SIV infection of other susceptible primate species, such as macaques, can cause chronic wasting syndromes and a disease similar to the human acquired immunodeficiency syndrome (AIDS)⁵–¹⁰. Because of the similarities between the human and nonhuman lentiviruses, SIV and its susceptible primate host have become the principal model for studying the pathogenesis of AIDS and developing…

Original language	English (US)
Pages (from-to)	172-177
Number of pages	6
Journal	New England Journal of Medicine
Volume	330
Issue number	3
DOIs	https://doi.org/10.1056/NEJM199401203300304
State	Published - Jan 20 1994

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1056/NEJM199401203300304

Cite this

Infection of a Laboratory Worker with Simian Immunodeficiency Virus. / Khabbaz, Rima F.; Heneine, Walid; George, J. Richard; Parekh, Bharat; Rowe, Thomas; Woods, Toni; Switzer, William M.; Mcclure, Harold M.; Murphey-Corb, Michael; Folks, Thomas M.

In: New England Journal of Medicine, Vol. 330, No. 3, 20.01.1994, p. 172-177.

Research output: Contribution to journal › Article › peer-review

@article{eef08fcd085845d58b6ee836453e9ecd,

title = "Infection of a Laboratory Worker with Simian Immunodeficiency Virus",

abstract = "Simian immunodeficiency viruses (SIVs) are primate lentiviruses that are morphologically similar and biologically related to human immunodeficiency viruses (HIVs)1–4. SIVs naturally infect some nonhuman primate species, such as African green monkeys and sooty mangabey monkeys, without causing immunodeficiency. In contrast, experimental SIV infection of other susceptible primate species, such as macaques, can cause chronic wasting syndromes and a disease similar to the human acquired immunodeficiency syndrome (AIDS)5–10. Because of the similarities between the human and nonhuman lentiviruses, SIV and its susceptible primate host have become the principal model for studying the pathogenesis of AIDS and developing…",

author = "Khabbaz, {Rima F.} and Walid Heneine and George, {J. Richard} and Bharat Parekh and Thomas Rowe and Toni Woods and Switzer, {William M.} and Mcclure, {Harold M.} and Michael Murphey-Corb and Folks, {Thomas M.}",

year = "1994",

month = jan,

day = "20",

doi = "10.1056/NEJM199401203300304",

language = "English (US)",

volume = "330",

pages = "172--177",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachussetts Medical Society",

number = "3",

}

TY - JOUR

T1 - Infection of a Laboratory Worker with Simian Immunodeficiency Virus

AU - Khabbaz, Rima F.

AU - Heneine, Walid

AU - George, J. Richard

AU - Parekh, Bharat

AU - Rowe, Thomas

AU - Woods, Toni

AU - Switzer, William M.

AU - Mcclure, Harold M.

AU - Murphey-Corb, Michael

AU - Folks, Thomas M.

PY - 1994/1/20

Y1 - 1994/1/20

N2 - Simian immunodeficiency viruses (SIVs) are primate lentiviruses that are morphologically similar and biologically related to human immunodeficiency viruses (HIVs)1–4. SIVs naturally infect some nonhuman primate species, such as African green monkeys and sooty mangabey monkeys, without causing immunodeficiency. In contrast, experimental SIV infection of other susceptible primate species, such as macaques, can cause chronic wasting syndromes and a disease similar to the human acquired immunodeficiency syndrome (AIDS)5–10. Because of the similarities between the human and nonhuman lentiviruses, SIV and its susceptible primate host have become the principal model for studying the pathogenesis of AIDS and developing…

AB - Simian immunodeficiency viruses (SIVs) are primate lentiviruses that are morphologically similar and biologically related to human immunodeficiency viruses (HIVs)1–4. SIVs naturally infect some nonhuman primate species, such as African green monkeys and sooty mangabey monkeys, without causing immunodeficiency. In contrast, experimental SIV infection of other susceptible primate species, such as macaques, can cause chronic wasting syndromes and a disease similar to the human acquired immunodeficiency syndrome (AIDS)5–10. Because of the similarities between the human and nonhuman lentiviruses, SIV and its susceptible primate host have become the principal model for studying the pathogenesis of AIDS and developing…

UR - http://www.scopus.com/inward/record.url?scp=0027957931&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027957931&partnerID=8YFLogxK

U2 - 10.1056/NEJM199401203300304

DO - 10.1056/NEJM199401203300304

M3 - Article

C2 - 8264739

AN - SCOPUS:0027957931

VL - 330

SP - 172

EP - 177

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 3

ER -

Infection of a Laboratory Worker with Simian Immunodeficiency Virus

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this