Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

Christina R. Robinson, Justin L. Martin, Lily Zhang, Russell M. Canham, Shuaib M. Abdullah, Joaquin E. Cigarroa, L. David Hillis, Sabina A. Murphy, Darren K. McGuire, James A. De Lemos, Ellen C. Keeley

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.

Original languageEnglish (US)
Pages (from-to)7-9
Number of pages3
JournalAmerican Journal of Cardiology
Volume97
Issue number1
DOIs
StatePublished - Jan 1 2006

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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