TY - JOUR
T1 - Increased incidence of type II diabetes mellitus in Mexican Americans
AU - Haffner, Steven M.
AU - Hazuda, Helen P.
AU - Mitchell, Braxton D.
AU - Patterson, Judith K.
AU - Stern, Michael P.
PY - 1991/2
Y1 - 1991/2
N2 - Objective: To determine whether Mexican Americans have an increased incidence of non-insulin-dependent (type II) diabetes mellitus relative to non-Hispanic whites. Currently, no study has reported on the incidence of this disorder in Mexican Americans. Research Design and Methods: We determined the 8-yr incidence of type II diabetes in 617 Mexican Americans and 306 non-Hispanic whites who participated in the San Antonio Heart Study, a population-based study of diabetes and cardiovascular disease. Forty Mexican Americans (6.5%) and 6 non-Hispanic whites (2%) developed type II diabetes, as defined by World Health Organization criteria. The age-adjusted ethnic odds ratio (OR; Mexican Americans/non-Hispanic whites) for diabetes incidence was 8.13 (95% confidence interval [C1] 1.10-59.9) in men and 3.62 (95% Cl 1.37-9.55) in women. We adjusted for age, sex, ethnicity, body mass index, and level of educational attainment with multiple logistic regression analyses. Results: Mexican Americans continued to show a statistically significant increase in diabetes incidence (OR 2.72, 95% Cl 1.02-7.28). Obesity and age were also positively related to diabetes incidence in this analysis (P < 0.001). In addition, subjects with at least some college education had a lower incidence of diabetes than those with less than a high school education (OR 0.51, 95% Cl 0.26-0.99). Conclusions: The incidence of type II diabetes in Mexican Americans is greater than in non-Hispanic whites, a difference that is not explained by ethnic differences in obesity, age, or level of educational attainment.
AB - Objective: To determine whether Mexican Americans have an increased incidence of non-insulin-dependent (type II) diabetes mellitus relative to non-Hispanic whites. Currently, no study has reported on the incidence of this disorder in Mexican Americans. Research Design and Methods: We determined the 8-yr incidence of type II diabetes in 617 Mexican Americans and 306 non-Hispanic whites who participated in the San Antonio Heart Study, a population-based study of diabetes and cardiovascular disease. Forty Mexican Americans (6.5%) and 6 non-Hispanic whites (2%) developed type II diabetes, as defined by World Health Organization criteria. The age-adjusted ethnic odds ratio (OR; Mexican Americans/non-Hispanic whites) for diabetes incidence was 8.13 (95% confidence interval [C1] 1.10-59.9) in men and 3.62 (95% Cl 1.37-9.55) in women. We adjusted for age, sex, ethnicity, body mass index, and level of educational attainment with multiple logistic regression analyses. Results: Mexican Americans continued to show a statistically significant increase in diabetes incidence (OR 2.72, 95% Cl 1.02-7.28). Obesity and age were also positively related to diabetes incidence in this analysis (P < 0.001). In addition, subjects with at least some college education had a lower incidence of diabetes than those with less than a high school education (OR 0.51, 95% Cl 0.26-0.99). Conclusions: The incidence of type II diabetes in Mexican Americans is greater than in non-Hispanic whites, a difference that is not explained by ethnic differences in obesity, age, or level of educational attainment.
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U2 - 10.2337/diacare.14.2.102
DO - 10.2337/diacare.14.2.102
M3 - Article
C2 - 2060411
AN - SCOPUS:0025853092
VL - 14
SP - 102
EP - 108
JO - Diabetes Care
JF - Diabetes Care
SN - 1935-5548
IS - 2
ER -