In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents

Nikolaos G. Almyroudis; Deanna A. Sutton; Annette W. Fothergill; Michael G. Rinaldi; Shimon Kusne

doi:10.1128/AAC.00452-07

In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents

Nikolaos G. Almyroudis, Deanna A. Sutton, Annette W. Fothergill, Michael G. Rinaldi, Shimon Kusne

Research output: Contribution to journal › Article › peer-review

195 Scopus citations

Abstract

We evaluated the in vitro susceptibilities of 217 zygomycetes to amphotericin B, ketoconazole, fluconazole, itraconazole, voriconazole, posaconazole, caspofungin, and flucytosine. The significant in vitro activity of posaconazole against several species appears to support its reported clinical efficacy. Decreased susceptibility to amphotericin B was noted with Cunninghamella bertholletiae.

Original language	English (US)
Pages (from-to)	2587-2590
Number of pages	4
Journal	Antimicrobial agents and chemotherapy
Volume	51
Issue number	7
DOIs	https://doi.org/10.1128/AAC.00452-07
State	Published - Jul 2007

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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