In vitro interaction of posaconazole and caspofungin against clinical isolates of Candida glabrata

E. R. Oliveira, A. W. Fothergill, W. R. Kirkpatrick, B. J. Coco, T. F. Patterson, S. W. Redding

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Combinations of caspofungin and posaconazole were evaluated by fractional inhibitory concentration index against 119 Candida glabrata isolates. Synergy was seen in 18% of all isolates and in 4% of fluconazole-resistant isolates at 48 h without evidence of antagonism. This antifungal combination may have utility against this organism.

Original languageEnglish (US)
Pages (from-to)3544-3545
Number of pages2
JournalAntimicrobial agents and chemotherapy
Volume49
Issue number8
DOIs
StatePublished - Aug 2005

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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