In vitro evaluation of voriconazole against some clinically important fungi

Michael R. McGinnis, Lester Pasarell, Deanna A. Sutton, Annette W. Fothergill, Chester R. Cooper, Michael G. Rinaldi

Research output: Contribution to journalArticle

110 Scopus citations

Abstract

Voriconazole was compared to amphotericin B, fluconazole, and itraconazole by using an in vitro macrobroth dilution test based upon current National Committee for Clinical Laboratory Standards tentative Standards against the dimorphic fungi and several opportunistic molds and yeasts. In all instances, the voriconazole MICs were lower than those of fluconazole. In most instances, the MICs were lower than the recorded MICs of amphotericin B and itraconazole.

Original languageEnglish (US)
Pages (from-to)1832-1834
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume41
Issue number8
DOIs
StatePublished - Aug 1997

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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    McGinnis, M. R., Pasarell, L., Sutton, D. A., Fothergill, A. W., Cooper, C. R., & Rinaldi, M. G. (1997). In vitro evaluation of voriconazole against some clinically important fungi. Antimicrobial agents and chemotherapy, 41(8), 1832-1834. https://doi.org/10.1128/aac.41.8.1832