In vitro comparison of heated saline-blood admixture with a heat exchanger for rapid warming of red blood cells

S. M. Cohn, G. E. Stack, J. M. Bergstein, C. W. Schwab, B. K. Paul

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We compared the rapidity of rewarming and infusing red blood cells (RBCs) mixed with 24°C, 50°C, and 60°C saline with the rapidity of administering undiluted RBCs through a heat exchanger. We measured flow rate, final temperature, and hemolysis in matched 41-45-day-old pooled AS-1 RBCs infused through high-flow tubing via a 14-gauge catheter under the influence of gravity. Undiluted RBCs were tested as controls. The final temperature of the 60°C admixture technique was lower than that with the heat exchanger (28.5 ± 0.2°C vs. 32.7 ± 0.2°C), but the flow rate was higher (258 ± 8 mL/min vs. 61 ± 4 mL/min). Admixture with 60°C saline resulted in no increase in hemolysis. This technique appears to be a simple, inexpensive method for rapid rewarming and infusion of RBCs and may be valuable for administration of RBCs simultaneously through multiple sites during resuscitation.

Original languageEnglish (US)
Pages (from-to)688-691
Number of pages4
JournalJournal of Trauma
Volume35
Issue number5
StatePublished - 1993
Externally publishedYes

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Hot Temperature
Erythrocytes
Rewarming
Hemolysis
Temperature
Gravitation
Resuscitation
In Vitro Techniques
Catheters

ASJC Scopus subject areas

  • Surgery

Cite this

Cohn, S. M., Stack, G. E., Bergstein, J. M., Schwab, C. W., & Paul, B. K. (1993). In vitro comparison of heated saline-blood admixture with a heat exchanger for rapid warming of red blood cells. Journal of Trauma, 35(5), 688-691.

In vitro comparison of heated saline-blood admixture with a heat exchanger for rapid warming of red blood cells. / Cohn, S. M.; Stack, G. E.; Bergstein, J. M.; Schwab, C. W.; Paul, B. K.

In: Journal of Trauma, Vol. 35, No. 5, 1993, p. 688-691.

Research output: Contribution to journalArticle

Cohn, SM, Stack, GE, Bergstein, JM, Schwab, CW & Paul, BK 1993, 'In vitro comparison of heated saline-blood admixture with a heat exchanger for rapid warming of red blood cells', Journal of Trauma, vol. 35, no. 5, pp. 688-691.
Cohn, S. M. ; Stack, G. E. ; Bergstein, J. M. ; Schwab, C. W. ; Paul, B. K. / In vitro comparison of heated saline-blood admixture with a heat exchanger for rapid warming of red blood cells. In: Journal of Trauma. 1993 ; Vol. 35, No. 5. pp. 688-691.
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