In vitro activity of aztreonam in combination with newer β-lactams and amikacin against multiply resistant gram-negative bacilli

M. A. Buesing, J. H. Jorgensen

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

The in vitro synergistic activity of aztreonam in combination with piperacillin, moxalactam, cefotaxime, cefoperazone, and amikacin was examined against multiply resistant isolates of the family Enterobacteriaceae and Pseudomonas aeruginosa. Aztreonam in combination with amikacin demonstrated synergy against 71% of the isolates, whereas combinations of aztreonam plus a second beta-lactam demonstrated synergy against 42% of the isolates.

Original languageEnglish (US)
Pages (from-to)283-285
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume25
Issue number2
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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