In vitro activity of aztreonam in combination with newer β-lactams and amikacin against multiply resistant gram-negative bacilli

M. A. Buesing, J. H. Jorgensen

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The in vitro synergistic activity of aztreonam in combination with piperacillin, moxalactam, cefotaxime, cefoperazone, and amikacin was examined against multiply resistant isolates of the family Enterobacteriaceae and Pseudomonas aeruginosa. Aztreonam in combination with amikacin demonstrated synergy against 71% of the isolates, whereas combinations of aztreonam plus a second beta-lactam demonstrated synergy against 42% of the isolates.

Original languageEnglish (US)
Pages (from-to)283-285
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume25
Issue number2
StatePublished - 1984

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Aztreonam
Lactams
Amikacin
Bacillus
Moxalactam
Cefoperazone
Piperacillin
Cefotaxime
beta-Lactams
Enterobacteriaceae
Pseudomonas aeruginosa
In Vitro Techniques

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

In vitro activity of aztreonam in combination with newer β-lactams and amikacin against multiply resistant gram-negative bacilli. / Buesing, M. A.; Jorgensen, J. H.

In: Antimicrobial Agents and Chemotherapy, Vol. 25, No. 2, 1984, p. 283-285.

Research output: Contribution to journalArticle

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