Impulsivity and BOLD fMRI activation in MDMA users and healthy control subjects

Ignacio H. Valdes, Joel L. Steinberg, Ponnada A. Narayana, Larry A. Kramer, Donald M. Dougherty, Alan C. Swann, Ernest S. Barratt, Frederick Gerard Moeller

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


The correlation between scores on the Barratt Impulsiveness Scale (BIS) and activation measured by functional magnetic resonance imaging in a dorsolateral prefrontal cortical (DLPFC) activating task was examined in 15 MDMA-using subjects and 19 controls. A significant correlation between BIS scores and DLPFC activation was found, supporting a role for the DLPFC in BIS-measured impulsivity.

Original languageEnglish (US)
Pages (from-to)239-242
Number of pages4
JournalPsychiatry Research - Neuroimaging
Issue number2-3
StatePublished - Oct 30 2006
Externally publishedYes


  • Impulsivity
  • Prefrontal
  • fMRI

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health


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