Improving the temporal resolution of functional MR imaging using keyhole techniques

Jia Hong Gao, Jinhu Xiong, Song Lai, E. Mark Haacke, Marty G. Woldorff, Jinqi Li, Peter T Fox

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Using a keyhole technique, it is shown that the data acquisition rate of gradient-echo imaging for functional MRI (fMRI) studies can be increased substantially. The resulting enhancement of the temporal resolution of fMRIs was accomplished without modifying the hardware of a conventional MRI system. High spatial resolution fMRI images were first collected with conventional full k-space acquisition and image reconstruction. Using the same data set, simulation reconstruction using the keyhole principle and zero-padding were performed for comparison with the full k-space reconstruction. No significant changes were found for fMRI images generated from the keyhole technique with a data sharing profile of 50% of the k-space. As k-space data sharing profiles increased to 75 and 87.5%, the keyhole fMRI images began to show only modest changes in activation intensity and area compared with the standard images. In contrast, zero-padding fMRI images produced a significant disparity both in activation intensity and area relative to the truly high- resolution fMRI images. The keyhole technique's ability to retain the intensity and area of fMRI information, while substantially reducing acquisition time, makes it a promising method for fMRI studies.

Original languageEnglish (US)
Pages (from-to)854-860
Number of pages7
JournalMagnetic Resonance in Medicine
Volume35
Issue number6
DOIs
StatePublished - Jun 1996

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Magnetic Resonance Imaging
Information Dissemination
Computer-Assisted Image Processing

Keywords

  • Functional MRI
  • keyhole
  • motor
  • temporal resolution

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Improving the temporal resolution of functional MR imaging using keyhole techniques. / Gao, Jia Hong; Xiong, Jinhu; Lai, Song; Haacke, E. Mark; Woldorff, Marty G.; Li, Jinqi; Fox, Peter T.

In: Magnetic Resonance in Medicine, Vol. 35, No. 6, 06.1996, p. 854-860.

Research output: Contribution to journalArticle

Gao, Jia Hong ; Xiong, Jinhu ; Lai, Song ; Haacke, E. Mark ; Woldorff, Marty G. ; Li, Jinqi ; Fox, Peter T. / Improving the temporal resolution of functional MR imaging using keyhole techniques. In: Magnetic Resonance in Medicine. 1996 ; Vol. 35, No. 6. pp. 854-860.
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