Improvement of the exercise test after therapy in thyrotoxic periodic paralysis

Carlayne E. Jackson, Richard J. Barohn

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


The diagnosis of periodic paralysis (PP) can be aided by demonstrating a decrease in compound motor action potential (CMAP) amplitude after several minutes of exercise. We report a case of secondary hypokalemic PP due to thyrotoxicosis in which the decrease in the CMAP amplitude after exercise dramatically improved after treatment, when a euthyroid state was achieved. The exercise test is a useful electropghysiologic means of monitoring the neuromuscular status of patients with thyrotoxic periodic paralysis prior to, and after treatment of the thyrotoxicosis.

Original languageEnglish (US)
Pages (from-to)1069-1071
Number of pages3
JournalMuscle & Nerve
Issue number10
StatePublished - Oct 1992


  • exercise test
  • hypokalemia
  • periodic paralysis
  • thyrotoxicosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)
  • Cellular and Molecular Neuroscience
  • Physiology


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