Implementing cardiovascular risk reduction in patients with cardiovascular disease and diabetes mellitus

Shailesh Nandish, Jamison Wyatt, Oscar Bailon, Mike Smith, Rene Oliveros, Robert Chilton

Research output: Contribution to journalReview article

21 Scopus citations

Abstract

The role of cardiovascular risk reduction in patients with diabetes mellitus is significant as several factors have been found to promote accelerated atherosclerosis in persons with diabetes including hyperglycemia-induced endothelial dysfunction, impaired fibrinolysis, increased platelet aggregation, plaque instability, dysfunctional arterial remodeling, and fibrotic and calcified coronary arteries. Recent attention has focused on identifying a cardiovascular biomarker that would propose a better noninvasive way to detect or visualize subclinical cardiovascular disease and prevent cardiovascular events. This article reviews the use of commonly used cardiovascular risk assessment tools and emerging biomarkers including coronary artery calcium scanning, metabolomics, genomics, and the role of optimal revascularization and risk reduction strategies and their impact on reducing risk in patients with cardiovascular disease and diabetes.

Original languageEnglish (US)
Pages (from-to)42B-51B
JournalAmerican Journal of Cardiology
Volume108
Issue number3 SUPPL.
DOIs
StatePublished - Aug 2 2011

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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