Implementation of the Prostate Cancer Prevention Trial (PCPT)

Phyllis J. Goodman, Catherine M. Tangen, John J. Crowley, Susan M. Carlin, Anne Ryan, Charles A. Coltman, Leslie G. Ford, Ian M. Thompson

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


The Prostate Cancer Prevention Trial is a randomized double blind chemoprevention trial of 18,882 men. It is designed to test the difference in the histologically proven prostate cancer prevalence between a group of participants given finasteride and another given placebo for 7 years. We present an overview of the study design, details of the administrative structure of the study and a description of the successful implementation of the accrual phase.

Original languageEnglish (US)
Pages (from-to)203-222
Number of pages20
JournalControlled Clinical Trials
Issue number2
StatePublished - Apr 2004


  • Chemoprevention
  • Finasteride
  • Prostate cancer
  • Study management
  • Study organization

ASJC Scopus subject areas

  • Pharmacology


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