TY - JOUR
T1 - Impact of new antifungal breakpoints on antifungal resistance in Candida species
AU - Fothergill, Annette W.
AU - Sutton, Deanna A.
AU - McCarthy, Dora I.
AU - Wiederhold, Nathan P.
PY - 2014/3
Y1 - 2014/3
N2 - We reviewed our antifungal susceptibility data for micafungin, anidulafungin, fluconazole, and voriconazole against Candida species and compared resistance rates determined by the previous and recently revised CLSI antifungal breakpoints. With the new breakpoints, resistance was significantly increased for micafungin (from 0.8% to 7.6%), anidulafungin (from 0.9% to 7.3%), and voriconazole (from 6.1% to 18.4%) against Candida glabrata. Resistance was also increased for fluconazole against Candida albicans (from 2.1% to 5.7%).
AB - We reviewed our antifungal susceptibility data for micafungin, anidulafungin, fluconazole, and voriconazole against Candida species and compared resistance rates determined by the previous and recently revised CLSI antifungal breakpoints. With the new breakpoints, resistance was significantly increased for micafungin (from 0.8% to 7.6%), anidulafungin (from 0.9% to 7.3%), and voriconazole (from 6.1% to 18.4%) against Candida glabrata. Resistance was also increased for fluconazole against Candida albicans (from 2.1% to 5.7%).
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U2 - 10.1128/JCM.03044-13
DO - 10.1128/JCM.03044-13
M3 - Article
C2 - 24403302
AN - SCOPUS:84894593134
SN - 0095-1137
VL - 52
SP - 994
EP - 997
JO - Journal of clinical microbiology
JF - Journal of clinical microbiology
IS - 3
ER -