TY - JOUR
T1 - Impact of hysterectomy on stress urinary incontinence
T2 - an identical twin study
AU - Miller, Jay James R.
AU - Botros, Sylvia M.
AU - Beaumont, Jennifer L.
AU - Aschkenazi, Sarit O.
AU - Gamble, Tondalaya
AU - Sand, Peter K.
AU - Goldberg, Roger P.
PY - 2008/5
Y1 - 2008/5
N2 - Objective: This study uses the unique properties of twin research design to evaluate whether hysterectomy impacts stress urinary incontinence (SUI). Study Design: As part of the Evanston Twins Sister Study, we performed bivariate and multivariate analyses on 83 identical twin pairs discordant for hysterectomy. Results: In bivariate analysis, SUI was less common in women who had prior hysterectomy (P =0.028). Multivariate analysis suggested that SUI was significantly less common after hysterectomy (odds ratio [OR], 0.55, confidence interval [CI], 0.30 to 1.00). Exclusion of twin pairs with a history of pelvic floor defect surgery eliminated the statistical relationship between hysterectomy and SUI (OR, 0.79, CI, 0.4 to 1.40). Conclusion: Hysterectomy, when analyzed with all cases, was associated with reduced SUI. When concurrent pelvic floor defect surgeries were excluded from the analysis, we found no relationship between hysterectomy and the risk of SUI afterward.
AB - Objective: This study uses the unique properties of twin research design to evaluate whether hysterectomy impacts stress urinary incontinence (SUI). Study Design: As part of the Evanston Twins Sister Study, we performed bivariate and multivariate analyses on 83 identical twin pairs discordant for hysterectomy. Results: In bivariate analysis, SUI was less common in women who had prior hysterectomy (P =0.028). Multivariate analysis suggested that SUI was significantly less common after hysterectomy (odds ratio [OR], 0.55, confidence interval [CI], 0.30 to 1.00). Exclusion of twin pairs with a history of pelvic floor defect surgery eliminated the statistical relationship between hysterectomy and SUI (OR, 0.79, CI, 0.4 to 1.40). Conclusion: Hysterectomy, when analyzed with all cases, was associated with reduced SUI. When concurrent pelvic floor defect surgeries were excluded from the analysis, we found no relationship between hysterectomy and the risk of SUI afterward.
KW - hysterectomy
KW - risk factors
KW - stress urinary incontinence
KW - twin studies
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U2 - 10.1016/j.ajog.2008.01.046
DO - 10.1016/j.ajog.2008.01.046
M3 - Article
C2 - 18455535
AN - SCOPUS:42949107571
SN - 0002-9378
VL - 198
SP - 565.e1-565.e4
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
IS - 5
ER -