Immunologic relationship between breast carcinoma and benign breast disease as detected by the leukocyte migration inhibition assay

G. B. Cannon, J. L. McCoy, L. J. Jerome, R. Reddick, C. Alford, V. Tinley, R. B. Herberman

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Patients with benign diseases of the breast reacted In a migration inhibition assay with extracts of breast cancer and benign breast lesions and a human breast cancer-derived cell line, MCF-7. The incidence of reactivity of the patients with benign breast diseases against these antigens was similar to that of breast cancer patients. In addition, patients with breast cancer reacted to some extracts of benign breast lesions. The reactivity occurred In patients with several different histopathologic types of breast lesions, but was not found In women with no detectable pathologic lesions.—J Natl Cancer Inst 61:1181-1186, 1978.

Original languageEnglish (US)
Pages (from-to)1181-1186
Number of pages6
JournalJournal of the National Cancer Institute
Volume61
Issue number5
DOIs
StatePublished - Nov 1978
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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