TY - JOUR
T1 - Immune system and bone remodeling
AU - Mundy, Gregory R.
N1 - Funding Information:
script of this article. This work is sup- ported by grants AR28149, AM07464, CA40035, RR01346, and DE08569 from the National Institutes of Health.
PY - 1990
Y1 - 1990
N2 - The skeleton undergoes continuous cellular remodeling in a manner similar to that of replacement of a wall, brick by brick. Products of immune cells are likely to modulate all of the cellular events involved in bone remodeling. The local factors that modulate bone cell function and bone remodeling-osteotropic cytokines or growth-regulatory factors-are similar to those involved in other body processes such as wound healing, immune function, oncogenesis, angiogenesis, and embryogenesis.
AB - The skeleton undergoes continuous cellular remodeling in a manner similar to that of replacement of a wall, brick by brick. Products of immune cells are likely to modulate all of the cellular events involved in bone remodeling. The local factors that modulate bone cell function and bone remodeling-osteotropic cytokines or growth-regulatory factors-are similar to those involved in other body processes such as wound healing, immune function, oncogenesis, angiogenesis, and embryogenesis.
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U2 - 10.1016/1043-2760(90)90069-F
DO - 10.1016/1043-2760(90)90069-F
M3 - Review article
AN - SCOPUS:0025333926
VL - 1
SP - 307
EP - 311
JO - Trends in Endocrinology and Metabolism
JF - Trends in Endocrinology and Metabolism
SN - 1043-2760
IS - 6
ER -