Immune system and bone remodeling

Gregory R. Mundy

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


The skeleton undergoes continuous cellular remodeling in a manner similar to that of replacement of a wall, brick by brick. Products of immune cells are likely to modulate all of the cellular events involved in bone remodeling. The local factors that modulate bone cell function and bone remodeling-osteotropic cytokines or growth-regulatory factors-are similar to those involved in other body processes such as wound healing, immune function, oncogenesis, angiogenesis, and embryogenesis.

Original languageEnglish (US)
Pages (from-to)307-311
Number of pages5
JournalTrends in Endocrinology and Metabolism
Issue number6
StatePublished - 1990

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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