Immune complexes in sjögren's syndrome

Michael Fischbach, Devron Char, Mary Christensen, Troy Daniels, Keith Whaley, Margaret Alspaugh, Norman Talal

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Sera from 48 patients with Sjögren's syndrome were examined for immune complexes by the Raji cell assay. There was no correlation between levels of immune complexes and the degree of lymphocytic infiltration of the labial salivary glands. Serum complement levels were normal. Five patients were serially followed during the development of pseudolymphoma or malignant lymphoma. Immune complex levels in 4 of the 5 patients were generally unchanged throughout the illness and did not parallel disease activity, rheumatoid factor, or SS‐A and SS‐B concentrations. Possible roles for immune complexes in Sjögren's syndrome are discussed.

Original languageEnglish (US)
Pages (from-to)791-795
Number of pages5
JournalArthritis & Rheumatism
Issue number7
StatePublished - Jul 1980
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)


Dive into the research topics of 'Immune complexes in sjögren's syndrome'. Together they form a unique fingerprint.

Cite this