Immune cell metabolism in autoimmunity

X. Teng, W. Li, C. Cornaby, L. Morel

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations

Abstract

Immune metabolism is a rapidly moving field. While most of the research has been conducted to define the metabolism of healthy immune cells in the mouse, it is recognized that the overactive immune system that drives autoimmune diseases presents metabolic abnormalities that provide therapeutic opportunities, as well as a means to understand the fundamental mechanisms of autoimmune activation more clearly. Here, we review recent publications that have reported how the major metabolic pathways are affected in autoimmune diseases, with a focus on rheumatic diseases.

Original languageEnglish (US)
Pages (from-to)181-192
Number of pages12
JournalClinical and Experimental Immunology
Volume197
Issue number2
DOIs
StatePublished - Aug 2019
Externally publishedYes

Keywords

  • B cell
  • T cells
  • autoimmunity
  • systemic lupus erythematosus

ASJC Scopus subject areas

  • General Medicine

Fingerprint

Dive into the research topics of 'Immune cell metabolism in autoimmunity'. Together they form a unique fingerprint.

Cite this