TY - JOUR
T1 - Immediate Angioplasty for Acute Myocardial Infarction
AU - Lange, Richard A
AU - Hillis, L. David
PY - 1993/3/11
Y1 - 1993/3/11
N2 - During the past 10 to 15 years, pathological and arteriographic studies have shown that Q-wave myocardial infarction is usually caused by an occlusive coronary arterial thrombus. Investigations have also shown that thrombolytic therapy can restore antegrade flow in the occluded artery, reduce the size of the infarct, and improve survival. Initially, thrombolytic agents were infused directly into the occluded coronary artery during cardiac catheterization, but later studies showed that intravenous administration offered similar efficacy without the delay, the need for angiographic equipment and skilled personnel, or the morbidity and mortality associated with emergency catheterization. Thus, effective therapy for evolving myocardial…
AB - During the past 10 to 15 years, pathological and arteriographic studies have shown that Q-wave myocardial infarction is usually caused by an occlusive coronary arterial thrombus. Investigations have also shown that thrombolytic therapy can restore antegrade flow in the occluded artery, reduce the size of the infarct, and improve survival. Initially, thrombolytic agents were infused directly into the occluded coronary artery during cardiac catheterization, but later studies showed that intravenous administration offered similar efficacy without the delay, the need for angiographic equipment and skilled personnel, or the morbidity and mortality associated with emergency catheterization. Thus, effective therapy for evolving myocardial…
UR - http://www.scopus.com/inward/record.url?scp=0027396901&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027396901&partnerID=8YFLogxK
U2 - 10.1056/NEJM199303113281010
DO - 10.1056/NEJM199303113281010
M3 - Editorial
C2 - 8433733
AN - SCOPUS:0027396901
VL - 328
SP - 726
EP - 728
JO - New England Journal of Medicine
JF - New England Journal of Medicine
SN - 0028-4793
IS - 10
ER -