Immediate Angioplasty for Acute Myocardial Infarction

Richard A. Lange, L. David Hillis

Research output: Contribution to journalEditorialpeer-review

40 Scopus citations

Abstract

During the past 10 to 15 years, pathological and arteriographic studies have shown that Q-wave myocardial infarction is usually caused by an occlusive coronary arterial thrombus. Investigations have also shown that thrombolytic therapy can restore antegrade flow in the occluded artery, reduce the size of the infarct, and improve survival. Initially, thrombolytic agents were infused directly into the occluded coronary artery during cardiac catheterization, but later studies showed that intravenous administration offered similar efficacy without the delay, the need for angiographic equipment and skilled personnel, or the morbidity and mortality associated with emergency catheterization. Thus, effective therapy for evolving myocardial…

Original languageEnglish (US)
Pages (from-to)726-728
Number of pages3
JournalNew England Journal of Medicine
Volume328
Issue number10
DOIs
StatePublished - Mar 11 1993

ASJC Scopus subject areas

  • Medicine(all)

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