Imaging and Screening of Hereditary Cancer Syndromes

Venkata S. Katabathina, Christine O. Menias, Srinivasa R. Prasad

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


There is a wide spectrum of mendelian disorders that predispose patients to an increased risk of benign as well as malignant tumors. Hereditary cancer syndromes are characterized by the early onset of diverse, frequently advanced malignancies in specific organ systems in multiple family members, posing significant challenges to diagnosis and management. A better understanding of the genetic abnormalities and pathophysiology that underlie these disorders has led to contemporary paradigms to screen, allowing early diagnosis, and has improved targeted therapies to aid in management. This article reviews select hereditary cancer syndromes with an emphasis on imaging-based screening and surveillance strategies.

Original languageEnglish (US)
Pages (from-to)1293-1309
Number of pages17
JournalRadiologic Clinics of North America
Issue number6
StatePublished - Nov 2017


  • Hereditary cancers
  • Imaging findings
  • Surveillance

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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