Identification of the telomeres on Schistosoma mansoni chromosomes by FISH

Hirohisa Hirai; Philip T. LoVerde

doi:10.2307/3284097

Identification of the telomeres on Schistosoma mansoni chromosomes by FISH

Hirohisa Hirai, Philip T. LoVerde

Biochemistry & Structural Biology

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The telomeres (molecular termini) of chromosomes play an important role in maintaining the structural integrity of the chromosome. Using a deoxyoligomer that contains the core sequence TTAGGG, we identified by fluorescence in situ hybridization (FISH) the telomeres on all 8 pairs of Schistosoma mansoni mitotic metaphase chromosomes. Our results indicate that S. mansoni exhibits a telomere sequence typical of other species.

Original language	English (US)
Pages (from-to)	511-512
Number of pages	2
Journal	Journal of Parasitology
Volume	82
Issue number	3
DOIs	https://doi.org/10.2307/3284097
State	Published - Jun 1996

ASJC Scopus subject areas

Parasitology
Ecology, Evolution, Behavior and Systematics

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title = "Identification of the telomeres on Schistosoma mansoni chromosomes by FISH",

abstract = "The telomeres (molecular termini) of chromosomes play an important role in maintaining the structural integrity of the chromosome. Using a deoxyoligomer that contains the core sequence TTAGGG, we identified by fluorescence in situ hybridization (FISH) the telomeres on all 8 pairs of Schistosoma mansoni mitotic metaphase chromosomes. Our results indicate that S. mansoni exhibits a telomere sequence typical of other species.",

author = "Hirohisa Hirai and LoVerde, {Philip T.}",

year = "1996",

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AB - The telomeres (molecular termini) of chromosomes play an important role in maintaining the structural integrity of the chromosome. Using a deoxyoligomer that contains the core sequence TTAGGG, we identified by fluorescence in situ hybridization (FISH) the telomeres on all 8 pairs of Schistosoma mansoni mitotic metaphase chromosomes. Our results indicate that S. mansoni exhibits a telomere sequence typical of other species.

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