Identification of platelet activating factor isolated from rabbit basophils as acetyl glyceryl ether phosphorylcholine

D. J. Hanahan, C. A. Demopoulos, J. Liehr, R. N. Pinckard

Research output: Contribution to journalArticle

289 Scopus citations

Abstract

Platelet activating factor obtained from antigen-stimulated rabbit buffy coat leukocytes containing 10% IgE-sensitized basophils was shown by gas-liquid chromatographic and mass spectrometric analysis of products after acetolysis and by base and acid hydrolysis to be acetyl-alkylglyceryl phosphorylcholine. The alkyl side chains were composed of octadecyl (>90%) and hexadecyl (<10%) residues.

Original languageEnglish (US)
Pages (from-to)5514-5516
Number of pages3
JournalJournal of Biological Chemistry
Volume255
Issue number12
StatePublished - Dec 1 1980

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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