Identification of intermediate filament keratin proteins in parakeratinized odontogenic keratocysts. A preliminary study

Charles F. Shuler, Brent J. Shriver

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The keratin proteins were extracted from the epithelial lining of three odontogenic keratocyst specimens. Two of the specimens were from a patient with nevoid basal cell carcinoma syndrome; the third was a solitary lesion. Seven keratin proteins with molecular weights of 46, 48, 50, 52, 54, 58, and 59 kilodaltons were identified by SDS-polyacrylamide gel electrophoresis and immunoblotting with antikeratin antiserum. The reproducibility of the pattern of molecular markers implies a series of genetic events coincident with the characteristic pattern of epithelial differentiation.

Original languageEnglish (US)
Pages (from-to)439-444
Number of pages6
JournalOral Surgery, Oral Medicine, Oral Pathology
Volume64
Issue number4
DOIs
StatePublished - Oct 1987
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dentistry(all)

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