Identification of intermediate filament keratin proteins in parakeratinized odontogenic keratocysts. A preliminary study

Charles F. Shuler, Brent J. Shriver

    Research output: Contribution to journalArticle

    10 Scopus citations

    Abstract

    The keratin proteins were extracted from the epithelial lining of three odontogenic keratocyst specimens. Two of the specimens were from a patient with nevoid basal cell carcinoma syndrome; the third was a solitary lesion. Seven keratin proteins with molecular weights of 46, 48, 50, 52, 54, 58, and 59 kilodaltons were identified by SDS-polyacrylamide gel electrophoresis and immunoblotting with antikeratin antiserum. The reproducibility of the pattern of molecular markers implies a series of genetic events coincident with the characteristic pattern of epithelial differentiation.

    Original languageEnglish (US)
    Pages (from-to)439-444
    Number of pages6
    JournalOral Surgery, Oral Medicine, Oral Pathology
    Volume64
    Issue number4
    DOIs
    StatePublished - Oct 1987

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    ASJC Scopus subject areas

    • Pathology and Forensic Medicine
    • Dentistry(all)

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