Identification of Differential Tumor Subtypes of T1 Bladder Cancer

A. Gordon Robertson, Clarice S. Groeneveld, Brian Jordan, Xiquo Lin, Kimberly A. McLaughlin, Arighno Das, Leigh Ann Fall, Damiano Fantini, Timothy J. Taxter, Lauren S. Mogil, Sia Viborg Lindskrog, Lars Dyrskjøt, David J. McConkey, Robert S. Svatek, Aurélien de Reyniès, Mauro A.A. Castro, Joshua J. Meeks

Research output: Contribution to journalArticlepeer-review

77 Scopus citations


We identified and characterized expression subtypes of high-grade T1 bladder cancer that are biologically heterogeneous and have variable responses to bacillus Calmette-Guérin treatment. We validated the subtypes and describe a single-patient classifier.

Original languageEnglish (US)
Pages (from-to)533-537
Number of pages5
JournalEuropean Urology
Issue number4
StatePublished - Oct 2020


  • Bacillus Calmette-Guérin
  • Carcinoma in situ
  • Immune signatures
  • Luminal
  • Non–muscle-invasive bladder cancer
  • Tumor subtype

ASJC Scopus subject areas

  • Urology


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