Identification of a human population infected with simian foamy viruses

Walid Heneine, William M. Switzer, Paul Sandstrom, Jennifer Brown, Shanmugam Vedapuri, Charles A. Schable, Arifa S. Khan, Nicholas W. Lerche, Matthias Schweizer, Dieter Neumann-Haefelin, Louisa E. Chapman, Thomas M. Folks

    Research output: Contribution to journalArticlepeer-review

    177 Scopus citations

    Abstract

    Studying the transmission of simian retroviruses to humans can help define the importance of these infections to public health. We identified a substantial prevalence (4/231, 1.8%) of infection with simian foamy viruses (SFV) among humans occupationally exposed to nonhuman primates. Evidence of SFV infection included seropositivity, proviral DNA detection and isolation of foamy virus. The infecting SFV originated from an African green monkey (one person) and baboons (three people). These Infections have not as yet resulted in either disease or sexual transmission, and may represent benign endpoint infections.

    Original languageEnglish (US)
    Pages (from-to)403-407
    Number of pages5
    JournalNature Medicine
    Volume4
    Issue number4
    DOIs
    StatePublished - Apr 1 1998

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

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