IACUC Review of nonhuman primate research

Suzette D. Tardif, Kristine Coleman, Theodore R. Hobbs, Corrine Lutz

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

This article will detail some of the issues that must be considered as institutional animal care and use committees (IACUCs) review the use of nonhuman primates (NHPs) in research. As large, intelligent, social, long-lived, and nondomesticated animals, monkeys are amongst the most challenging species used in biomedical research and the duties of the IACUC in relation to reviewing research use of these species can also be challenging. Issues of specific concern for review of NHP research protocols that are discussed in this article include scientific justification, reuse, social housing requirements, amelioration of distress, surgical procedures, and humane endpoints. Clear institutional policies and procedures as regards NHP in these areas are critical, and the discussion of these issues presented here can serve as a basis for the informed establishment of such policies and procedures.

Original languageEnglish (US)
Article numberilt040
Pages (from-to)234-245
Number of pages12
JournalILAR Journal
Volume54
Issue number2
DOIs
StatePublished - Nov 2013

Keywords

  • Distress
  • Iacuc
  • Nonhuman primate
  • Social housing
  • Surgery

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Biochemistry, Genetics and Molecular Biology(all)

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