Hypothetical protein Cpn0308 is localized in the Chlamydm pneumoniae inclusion membrane

Jianhua Luo, Tianjun Jia, Rhonda Flores, Ding Chen, Guangming Zhong

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The hypothetical protein encoded by Chlamydia pneumoniae open reading frame cpn0308 was detected in inclusion membranes of C. pneumoniae-infected cells using antibodies raised with Cpn0308 fusion proteins. The anti-Cpn0308 antibodies did not cross-react with IncA, a known C. pneumoniae inclusion membrane protein, although the anti-Cpn0308 antibody staining overlapped with the anti-IncA antibody labeling. The labeling of the inclusion membrane by the anti-Cpn0308 antibody was specifically blocked by the Cpn0308 but not IncA fusion proteins. The Cpn0308 antigen was detectable 24 h after infection and remained in the inclusion membrane throughout the infection course.

Original languageEnglish (US)
Pages (from-to)497-503
Number of pages7
JournalInfection and immunity
Volume75
Issue number1
DOIs
StatePublished - Jan 2007

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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