Hypoglycemia-induced hypertension in a diabetic patient on metoprolol

A. M.M. Shepherd, M. S. Lin, T. K. Keeton

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Metoprolol is the only cardioselective (β1) beta-adrenergic antagonist approved for use in the United States. This agent may be preferable to nonselective β-adrenergic blocking agents in stressful situations in which nonselective β1 and β2 blockade would permit unopposed epinephrine induced α-adrenergic vasoconstriction and hypertension. Because insulin-induced hypoglycemia may result in elevated levels of epinephrine, metoprolol has been recommended for use in diabetic hypertensive patients in preference to propranolol. We report a case of severe hypertension induced by hypoglycemia in a diabetic hypertensive patient receiving metoprolol.

Original languageEnglish (US)
Pages (from-to)357-358
Number of pages2
JournalAnnals of internal medicine
Issue number3
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Internal Medicine


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