Hydroxylated 2,3-diarylindenes: Synthesis, estrogen receptor binding affinity, and binding orientation considerations

Chemistry

• Estrogen 71%
• Kd 71%
• Hydroxylation 57%
• Ligand 42%
• Binding Site 28%
• Receptor Binding Affinity 28%
• Electron Particle 28%
• Hydroxyl 28%
• Electron Affinity 28%
• Estradiol 14%
• Indene 14%
• Cyclization Reaction 14%
• Hydroxyl Group 14%
• Non Steroidal Estrogen 14%
• Cyclic Structure 14%
• Radiometry 14%
• Assay 14%
• Synthesis (Chemical) 14%
• Hydrogen Bonding 14%

Biochemistry, Genetics and Molecular Biology

• Binding Affinity 100%
• Estrogen Receptor 71%
• Receptor Binding 57%
• Hydroxylation 57%
• Electron 28%
• Binding Site 28%
• Reduction (Chemistry) 28%
• Estradiol 14%
• Cyclization 14%
• Synthesis 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Receptor 42%
• Ligand 42%
• Hydroxyl Group 42%
• Binding Site 28%
• Diethylstilbestrol 14%
• Hydrogen 14%
• Indene 14%
• Estrogen 14%
• Biphenyl 14%